Clyde's life changes dramatically when his friend Sparser, driving Clyde, Hortense, and other friends back from a secluded rendezvous in the country in his boss's car, used without permission, hits a little girl and kills her. Fleeing from the police at high speed, Sparser crashes the car. Everyone but Sparser and his partner flee the scene of the crime. Clyde leaves Kansas City, fearing prosecution as an accessory to Sparser's crimes. This pattern of personal irresponsibility and panicked decision-making in Clyde's life recurs in the story, culminating in the central tragedy of the novel.
